Meyer Stem Cell Research Lab

Welcome to the Meyer Stem Cell Research Lab website. The goal of our research is to understand the fundamental mechanisms underlying the development of retinal neurons, as well as those processes that adversely affect these cells in blinding disorders. To accomplish these goals, we utilize genetically reprogrammed human induced pluripotent stem cells and direct their differentiation so that they become cells of the retina, such as photoreceptors, retinal pigment epithelium, and retinal ganglion cells.

By generating retinal cells from induced pluripotent stem cells, new and exciting possibilities for research now exist. Using these cells, we are now capable of studying some of the earliest events in the development of the human retina in a culture dish, which would otherwise be inaccessible for investigation. Furthermore, by estabishing induced pluripotent stem cells from patients with known genetically inherited degenerative diseases, it is now possible to study the progression of the disease within these cells, and potentially develop new approaches to the treatment of these diseases.

 

Recent News:

March 2016 - The Meyer Lab has a new manuscript published detailing our derivation of retinal ganglion cells from iPS cells, including the use of these cells for in vitro studies of glaucoma. Check out the paper here.

March 2016 - The Meyer Lab has published a new manuscript detailing the use of mRNA cellular reprogramming strategies for the development of retinal neurons. The paper is published in the journal Stem Cells Translational Medicine and can be viewed here.

February 2016 - PhD student Akshaya Sridhar has been profiled by the graduate school as a "Student Success" story. Check it out here. Congrats Akshaya!

September 2015 - Graduate student Sarah Ohlemacher has been awarded a best poster prize at the recent annual meeting of the Indiana Clinical and Translational Sciences Institute! Congrats Sarah!

See more news here....

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